Year : 2014 | Volume
: 1 | Issue : 1 | Page : 3--11
Central auditory plasticity indexed by mismatch negativity
Abdel-Hamid Elshintinawy, Enaas Kolkaila, Takwa A Gabr
Department of Otolaryngology, Audiology Unit, Head and Neck Surgery, Tanta University Hospitals, Tanta, Egypt
Unilateral hearing loss (UHL) represents a particular model for investigating the functional auditory plasticity in humans. Normally, monaural stimulation produces a normal pattern of a contralateral dominance. With UHL, this pattern changes.
The aim of the study was to investigate the effects of UHL side and age at onset on auditory processing.
Mismatch negativity (MMN) was recorded in response to speech and tone stimuli.
This study included two groups: the control (50 bilateral normal hearing) and study (206 UHL patients) groups. This group was further classified according to UHL side and age at UHL onset.
In controls, higher speech-evoked MMN amplitude was recorded in the right ear. The study group showed impaired speech-evoked MMN in either left or right UHL patients, especially in early onset UHL patients. Tone-evoked MMN was not affected in controls or UHL patients.
Cortical reorganization induced by UHL occurs mainly in patients with left-side affection. Speech processing is affected in UHL irrespective of the affected side, especially in early onset patients.
Takwa A Gabr
Audiology Unit, Department of Otolaryngology, Head and Neck Surgery, Tanta University Hospitals, Tanta
|How to cite this article:|
Elshintinawy AH, Kolkaila E, Gabr TA. Central auditory plasticity indexed by mismatch negativity.Adv Arab Acad Audio-Vestibul J 2014;1:3-11
|How to cite this URL:|
Elshintinawy AH, Kolkaila E, Gabr TA. Central auditory plasticity indexed by mismatch negativity. Adv Arab Acad Audio-Vestibul J [serial online] 2014 [cited 2020 Nov 23 ];1:3-11
Available from: http://www.aaj.eg.net/article.asp?issn=2314-8667;year=2014;volume=1;issue=1;spage=3;epage=11;aulast=Elshintinawy;type=0